In Star Wars Villainous: Scum and Villainy, players choose to play one of three iconic villains from the Star Wars galaxy, i​ncluding Boba Fett. Depending on their villain's unique power, players will use their villain's "ambition" to perform actions that power effects based on the villain's use of the Force, strategic leadership, or sheer luck. The game also incorporates villain-specific missions and rules for iconic ships and transports from all corners of the Star Wars galaxy.

Villains in Star Wars Villainous: Scum and Villainy can be mixed with those in Star Wars Villainous: Power of the Dark Side or used on their own in this game.